Thursday, March 24, 2016

Can Marijuana Cure Epileptic Seizures?

Perhaps you’ve seen a news clip such as CNN’s report about Charlotte Figi, or you caught a rerun of this episode of the Thom Hartmann radio show, about how patients tried everything to get rid of their seizures, and nothing worked — or even worse, the side effects made life even more dramatically hard than it already was with seizures. Until they tried CBD cannabis, that is. And now they’ve been seizure-free for years. These case studies provide hope for those living with epilepsy, which , according to CURE, or Citizens United for Research in Epilepsy, the figures are an “estimated 3 million Americans and 65 million people worldwide.”
Yet, as with much cannabis research, data is sparse because marijuana legalization has only recently started to take hold — at writing time, about half of the states in the US have legalized it for medical purposes. Even though relief from seizures might come only from CBD, and not THC — the psychotrophic (or “high” inducing) cannabis, since the US does not differentiate between types of cannabis use for legal reasons, if it’s cannabis, it’s ruled out. But epilepsy’s anecdotal successes are so clear that they became known as the “poster child” for medical marijuana. If an adult or child who has suffered seizures for years, but starts to use cannabis as a cure and immediately has no more suffering, the results do not seem coincidental.
The Epilepsy Foundation, an advocacy organization, toggles the line by stating that cannabis solutions should be pursued only if conventional medicines are unhelpful. Its stance references one study (presented at the Academy of Neurology, April 22, 2015, Washington DC) based on data from 137 subjects who used a pharmaceutical drug containing CBD, called Epidiolex. The study found that taking Epidiolex reduced the number of seizures for most people, and only 14 subjects (i.e. around 10%) withdrew due to the drug not affecting them. On the one hand, the Epilepsy Foundation encourages more large-scale research because this study was done on a small sample of people, and only looked at one drug. On the other hand, the Foundation outright advocates for cannabis’s legal use for medical solutions to epilepsy, as stated: “If a patient and their healthcare professionals feel that the potential benefits of medical cannabis for uncontrolled epilepsy outweigh the risks, then families need to have that legal option. Nothing should stand in the way of patients gaining access to this potentially lifesaving treatment.”
Since small-scale studies and anecdotal evidence can be indicative of larger-scale cure success rates, we encourage anyone suffering from epilepsy to seek out medical cannabis as an option. At present, this might mean moving states to live in an area where medical marijuana is legal. Is this not worth it?
If you would like to read Medical Marijuana’s report on epilepsy, including references to studies on medical marijuana’s effects, as well as a list of best strains to treat epilepsy/seizure disorders, click here.
Originally published at www.medicalmarijuana.com on March 24, 2016.

Thursday, February 18, 2016

Is Marijuana Safe During Pregnancy?


Nausea. Anxiety. Pain. These symptoms are part of most women’s pregnancies, often defining them for the entire nine months. Since marijuana can help these symptoms, and is now legal in several states, pregnant women are starting to beg the question: Could marijuana be medically useful for the nausea, the anxiety, and the pain? But if so, would it be dangerous for my baby?

For discussion purposes, we will look at two reports.

1) A December 2015 abstract from the NIH’s PubMed.gov (under the auspices of the national biotech research center) says don’t even go there. Evidence is lacking to prove marijuana is safe during pregnancy, and all the more so, past studies indicate that marijuana could be dangerous for the fetus. Complications center around “problems with neurological development, resulting in hyperactivity, poor cognitive function, and changes in dopaminergic receptors,” the report says.

2) A report by labor support doula Pamela McColl in the homebirth midwifery Birth Institute reviewed several studies dating between 1975 and 2011, and concluded similarly to the PubMed.gov abstract, stating outright, “Marijuana use during pregnancy interrupts fetal brain development.”

While both of these reports conclude that pregnant women should not use marijuana, neither of them can say that it is 100% dangerous. The PubMed.gov report admits that studies have not been comprehensive, and the studies cited by McCall are older and do not all examine cannabis usage during pregnancy per se.

More Questions Remain
 

 All things considered, perhaps pregnant women are missing out if marijuana could be deemed safe, in quantity and quality, for them and their babies. As a related matter on the feminine front, a recently-released cannabis product called Fiora Relief garnered viral attention for its cures for premenstrual and menstrual cramps. Stick the cannabis suppository up the vagina, and voila, those wrenchingly-heavy, stop-you-in-your-tracks uterine pangs and lower back aches are gone.
Wait a minute. Menstrual cramps are mini uterine contractions. So could this solution do the trick for the really heavy labor contractions? After all, it can also be inserted rectally. At this point it’s unlikely anyone in the conventional medical community will suggest this because the effects of a cannabis suppository, even rectally, might risk the baby getting high and affecting the heart rate. Another question is whether cannabis for pain relief would be any safer than other medical pain relief, such as epidurals, which can also affect heart rate. We do not mean to imply the safety of either option, rather to raise the question of statistical probability of risks when comparing marijuana usage to accepted modern medicine norms.

No for Now

All told, to date, the safety of marijuana usage in pregnancy is toggling the line of opening up a can of worms. Like many pregnancy safety questions, researchers and doctors understandably are leery of giving a definitive answer because there’s a developing baby involved. As such, the answer — like the blanket US medical stance on alcohol consumption during pregnancy — is “since we can’t know, the answer is no.” In other words, the better-safe-than-sorry approach is the official medical word. Pregnant women are advised against using marijuana routinely during pregnancy, legalities notwithstanding. What people try on their own has been, and remains, another story.

Originally published at www.medicalmarijuana.com on February 18, 2016.